Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 11/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009745 | 0.86 | RAB9A (0.59) | ERN1RAB9AKDM4EGAASMN1; SMN2 | |
| SCHEMBL454793 | 0.81 | CDC7 (0.59) | CDC7DBF4KDM4EKMT2AMEN1 | |
| SCHEMBL29627451 | 0.81 | CDC7 (0.59) | CDC7DBF4KDM4EKMT2AMEN1 | |
| SCHEMBL9275546 | 0.80 | XDH (0.53) | HTR2CCDC7DBF4RAB9AKDM4E | |
| SCHEMBL9281637 | 0.80 | XDH (0.56) | HTR2CRAB9AKDM4EGAASMN1; SMN2 | |
| SCHEMBL9278519 | 0.79 | CDC7 (0.57) | HTR2CCDC7DBF4RAB9AKDM4E | |
| SCHEMBL12454256 | 0.78 | ERN1 (0.42) | ERN1RAB9AKDM4EGAASMN1; SMN2 | |
| SCHEMBL15130562 | 0.76 | ERN1 (0.47) | ERN1 | |
| SCHEMBL12767074 | 0.72 | ERN1 (1.00) | ERN1 | |
| SCHEMBL12725676 | 0.71 | HTR2C (0.52) | HTR2CCDC7DBF4RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012073259-A1 | NOVEL PROCESS FOR THE PREPARATION OF FEBUXOSTAT | INDOCO REMEDIES LIMITED (IN) | 2012-06-07 | — | — | WO | disclosed |