Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20477374 | 0.85 | RNASEH1 (0.47) | RNASEH1CYP1A2SMN1; SMN2RXFP1L3MBTL1 | |
| SCHEMBL20477354 | 0.85 | ADCY10 (0.43) | RNASEH1ADCY10RXFP1PLA2G2AHDAC6 | |
| SCHEMBL22079307 | 0.83 | RNASEH1 (0.57) | RNASEH1CYP1A2SMN1; SMN2RXFP1L3MBTL1 | |
| SCHEMBL20477364 | 0.81 | RNASEH1 (0.44) | RNASEH1CYP1A2SMN1; SMN2ADCY10RXFP1 | |
| SCHEMBL21332907 | 0.77 | RNASEH1 (0.43) | RNASEH1CYP1A2SMN1; SMN2RXFP1L3MBTL1 | |
| SCHEMBL20477334 | 0.77 | ADCY10 (0.38) | RNASEH1ADCY10RXFP1L3MBTL1PLA2G2A | |
| SCHEMBL20477331 | 0.77 | ADCY10 (0.38) | RNASEH1ADCY10RXFP1L3MBTL1PLA2G2A | |
| SCHEMBL20477232 | 0.77 | RNASEH1 (0.41) | RNASEH1CYP1A2SMN1; SMN2RXFP1L3MBTL1 | |
| SCHEMBL20477235 | 0.77 | RNASEH1 (0.41) | RNASEH1CYP1A2SMN1; SMN2RXFP1L3MBTL1 | |
| SCHEMBL13218114 | 0.74 | MAPT (0.48) | RNASEH1RXFP1HDAC6PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313724-B1 | Bis (acyloxymethyl) imidazole Derivative | UNIV NEW YORK STATE RES FOUND (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5329012-A | Bactericides, fungicides or antitumor agents | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-07-12 | — | — | US | disclosed |
| EP-0313724-A2 | Bis (acyloxymethyl) imidazole Derivative | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1989-05-03 | — | — | EP | disclosed |