Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20477334 | 1.00 | ADCY10 (0.38) | ADCY10RXFP1RNASEH1L3MBTL1MAPK8 | |
| SCHEMBL20477232 | 0.82 | RNASEH1 (0.41) | RXFP1RNASEH1L3MBTL1NPSR1PLA2G2A | |
| SCHEMBL20477235 | 0.82 | RNASEH1 (0.41) | RXFP1RNASEH1L3MBTL1NPSR1PLA2G2A | |
| SCHEMBL9280321 | 0.77 | RNASEH1 (0.48) | ADCY10RXFP1RNASEH1L3MBTL1PLA2G2A | |
| SCHEMBL20477354 | 0.76 | ADCY10 (0.43) | ADCY10RXFP1RNASEH1MAPK8PLA2G2A | |
| SCHEMBL20477383 | 0.70 | CDC25A (0.42) | NPSR1PLA2G2ADRD2TBXA2R | |
| SCHEMBL25310115 | 0.69 | AADAT (0.35) | L3MBTL1 | |
| SCHEMBL25310112 | 0.69 | AADAT (0.35) | L3MBTL1 | |
| SCHEMBL25883500 | 0.69 | SMN1; SMN2 (0.44) | L3MBTL1NPSR1NPC1RAB9APKM | |
| SCHEMBL20477374 | 0.69 | RNASEH1 (0.47) | RXFP1RNASEH1L3MBTL1PLA2G2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108431004-B | Heterocyclic compounds | 武田药品工业株式会社 | 2021-02-12 | — | — | CN | disclosed |
| US-10787462-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-09-29 | — | — | US | disclosed |
| EP-3366684-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |
| US-20180319819-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-11-08 | — | — | US | disclosed |
| EP-3366684-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787462-B2 | Heterocyclic compound | RIPK1, RIPK4, RIPK3 | ADCY10 367/4885RXFP1 1437/4885RNASEH1 1143/4885 |
| US-20180319819-A1 | HETEROCYCLIC COMPOUND | RIPK1, RIPK4, RIPK3 | ADCY10 367/4885RXFP1 1437/4885RNASEH1 1143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.