Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527555 | 0.73 | KIF11 (0.51) | MAOBAOC3KIF11PPARGPPARA | |
| SCHEMBL23519064 | 0.71 | PPARG (0.51) | PPARGPPARAKDM4EMRGPRX4ALDH1A1 | |
| SCHEMBL9546526 | 0.71 | L3MBTL1 (0.55) | MAOBKIF11PPARGPPARAL3MBTL1 | |
| SCHEMBL7797664 | 0.70 | KIF11 (0.41) | KIF11TAAR1 | |
| SCHEMBL4008943 | 0.70 | PPARG (0.52) | PPARGPPARAKDM4EMRGPRX4ALDH1A1 | |
| SCHEMBL10599070 | 0.70 | TSHR (0.45) | MAOBAOC3PPARGPPARAKDM4E | |
| SCHEMBL2737127 | 0.70 | L3MBTL1 (0.47) | MAOBAOC3PPARGPPARAKDM4E | |
| SCHEMBL3524104 | 0.69 | L3MBTL1 (0.59) | MAOBAOC3KDM4EMRGPRX4L3MBTL1 | |
| SCHEMBL3054166 | 0.69 | TAAR1 (0.45) | KIF11KDM4ETAAR1ALDH1A1 | |
| SCHEMBL4214531 | 0.69 | TSHR (0.54) | MAOBAOC3PPARGPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514694-A | ENZYME INHIBITORS | GEORGIA TECH RESEARCH CORP (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0650368-A1 | USE OF CALPAIN INHIBITORS IN THE INHIBITION AND TREATMENT OF MEDICAL CONDITIONS ASSOCIATED WITH INCREASED CALPAIN ACTIVITY | CORTEX PHARMACEUTICALS, INC. (US) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994000095-A2 | USE OF CALPAIN INHIBITORS IN THE INHIBITION AND TREATMENT OF MEDICAL CONDITIONS ASSOCIATED WITH INCREASED CALPAIN ACTIVITY | CORTEX PHARMACEUTICALS, INC. (US) | 1994-01-06 | — | — | WO | disclosed |