Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2080135 | 0.98 | IDO1 (0.55) | TSHRMAPK1IDO1KDM4EMAOB | |
| SCHEMBL9798371 | 0.82 | LTA4H (0.54) | TSHRMAPK1IDO1KDM4EMAOB | |
| SCHEMBL15889136 | 0.78 | CYP3A4 (0.47) | MAPK1LMNAPKMHSD17B10L3MBTL1 | |
| SCHEMBL11527555 | 0.78 | KIF11 (0.51) | TSHRMAPK1IDO1KDM4EMAOB | |
| SCHEMBL29782607 | 0.78 | L3MBTL1 (0.58) | TSHRMAPK1KDM4EMAOBLMNA | |
| SCHEMBL19890691 | 0.78 | MGLL (0.48) | TSHRMAPK1IDO1KDM4EMAOB | |
| SCHEMBL5608697 | 0.78 | TSHR (0.48) | TSHRMAPK1IDO1KDM4EMAOB | |
| SCHEMBL167016 | 0.78 | L3MBTL1 (0.58) | TSHRMAPK1KDM4EMAOBLMNA | |
| SCHEMBL535445 | 0.78 | TSHR (0.48) | TSHRMAPK1IDO1KDM4EMAOB | |
| SCHEMBL27579381 | 0.78 | LTA4H (0.59) | TSHRMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051346-A1 | BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2025-02-13 | — | — | US | disclosed |
| WO-2023114858-A1 | BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114858-A1 | BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| US-10035790-B2 | RORγ modulators | EXELIXIS, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20150266856-A1 | RORGamma Modulators | EXELIXIS, INC. | 2015-09-24 | — | — | US | disclosed |
| US-20090054629-A1 | Inhibitors of Transthyretin Amyloid Fibril Formation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-02-26 | — | — | US | disclosed |
| US-20090054629-A1 | Inhibitors of Transthyretin Amyloid Fibril Formation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-02-26 | — | — | US | disclosed |
| US-7312361-B2 | Inhibitors of transthyretin amyloid fibril formation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312361-B2 | Inhibitors of transthyretin amyloid fibril formation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-12-25 | — | — | US | disclosed |
| US-20060178527-A1 | Inhibitors of transthyretin amyloid fibril formation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-08-10 | — | — | US | disclosed |
| EP-0119892-A1 | Hydroxyl amine derivatives, their preparation, their use as growth factors for vegetables and compositions thereof | ROUSSEL-UCLAF (FR) | 1984-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266856-A1 | RORGamma Modulators | RORB, RORA, RORC | TSHR 227/4885MAPK1 3204/4885IDO1 1596/4885 |
| US-10035790-B2 | RORγ modulators | RORB, RORA, RORC | TSHR 220/4885MAPK1 3109/4885IDO1 916/4885 |
| US-20090054629-A1 | Inhibitors of Transthyretin Amyloid Fibril Formation | TTR, TTPA, APOB | TSHR 1585/4885MAPK1 3987/4885IDO1 3718/4885 |
| US-20250051346-A1 | BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF | GAP43, BDNF, DBH | TSHR 4465/4885MAPK1 2218/4885IDO1 3858/4885 |
| US-20060178527-A1 | Inhibitors of transthyretin amyloid fibril formation | TTR, TTPA, APOB | TSHR 1585/4885MAPK1 3987/4885IDO1 3718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.