Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 2/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.56 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.56 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.56 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155032 | 0.79 | SCN2A (0.64) | SCN2ASIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4985451 | 0.74 | SIGMAR1 (0.50) | SCN2ASIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9283258 | 0.73 | PABPC1 (0.54) | SIGMAR1PABPC1CRHBPCRHR2KEAP1 | |
| SCHEMBL1273875 | 0.72 | SIGMAR1 (1.00) | SCN2ASIGMAR1GRIN2DGRIN3BGRIN1 | |
| Bromide SCHEMBL5055196 | 0.71 | PABPC1 (0.53) | SIGMAR1PABPC1CRHBPCRHR2KEAP1 | |
| Hydrochloric Acid SCHEMBL9438295 | 0.71 | SIGMAR1 (0.97) | SCN2ASIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6628883 | 0.70 | PABPC1 (0.59) | PABPC1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL4977834 | 0.70 | SCN2A (0.74) | SCN2ASIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28682214 | 0.69 | CYP1A2 (0.65) | PABPC1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL30358056 | 0.69 | SCN2A (1.00) | SCN2ASIGMAR1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995020950-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1995-08-10 | — | — | WO | disclosed |