Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666316 | 0.89 | TSHR (0.48) | ADRB1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL15545669 | 0.84 | HTR6 (0.44) | ADRB1HTR1AHTR2ABACE1HTR6 | |
| SCHEMBL5563018 | 0.84 | MAPK1 (0.51) | ADRB1DRD2DRD3DRD4HTR3E | |
| SCHEMBL1742847 | 0.84 | ADRB1 (0.51) | ADRB1DRD2DRD3HTR1AHTR2A | |
| SCHEMBL5563304 | 0.83 | ALDH1A1 (0.46) | ADRB1DRD2DRD4HTR2CBACE1 | |
| SCHEMBL5564533 | 0.82 | BACE1 (0.44) | ADRB1HTR1AHTR2ABACE1HTR3E | |
| SCHEMBL8623037 | 0.82 | BACE1 (0.51) | ADRB1DRD2DRD3HTR1AHTR2A | |
| SCHEMBL27818370 | 0.81 | ADRB1 (0.51) | ADRB1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL16230836 | 0.80 | PRMT5 (0.44) | ADRB1HTR1AHTR2ABACE1HTR6 | |
| SCHEMBL8092711 | 0.79 | ITGB3 (0.43) | HTR1AHTR2ABACE1HTR6HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030659-A1 | BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINERGIC AGENTS, ESP. SELECTIVE FOR THE DOPAMINE D3 RECEPTOR | WARNER-LAMBERT COMPANY (US) | 1995-11-16 | — | — | WO | disclosed |