Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | HTR1A | P08908 | 1/20 | 0.74 |
| ▸ | MAOA | P21397 | 1/20 | 0.74 |
| ▸ | MAOB | P27338 | 1/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.74 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.74 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 3/20 | 0.61 |
| ▸ | DRD4 | P21917 | 3/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | PHGDH | O43175 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Moclobemide SCHEMBL49708 | 0.85 | CD274 (1.00) | ALDH1A1HTR1AMAOAMAOBKCNH2 | |
| Moclobemide SCHEMBL3408310 | 0.85 | CD274 (1.00) | ALDH1A1HTR1AMAOAMAOBKCNH2 | |
| SCHEMBL13492542 | 0.85 | KMT2A (0.71) | ALDH1A1HTR1AMAOAMAOBKCNH2 | |
| SCHEMBL2228237 | 0.84 | ALDH1A1 (0.66) | ALDH1A1HTR1AMAOAMAOBKCNH2 | |
| Moclobemide SCHEMBL11475483 | 0.84 | CD274 (0.97) | ALDH1A1HTR1AMAOAMAOBKCNH2 | |
| SCHEMBL12090046 | 0.84 | LMNA (0.58) | ALDH1A1HTR1AMAOAMAOBKCNH2 | |
| Eprobemide SCHEMBL570896 | 0.83 | ALDH1A1 (0.85) | ALDH1A1HTR1AMAOAMAOBKCNH2 | |
| Eprobemide SCHEMBL10495496 | 0.82 | ALDH1A1 (0.82) | ALDH1A1HTR1AMAOAMAOBKCNH2 | |
| SCHEMBL8297748 | 0.77 | ALDH1A1 (0.66) | ALDH1A1HTR1AMAOAMAOBKCNH2 | |
| SCHEMBL21024443 | 0.76 | RAB9A (1.00) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420644-B2 | Pharmaceutical composition intended for the prevention or for the treatment of cerebral oedemas | BIOCODEX (FR) | 2013-04-16 | — | — | US | disclosed |