Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1418773 | 0.77 | CYP2C19 (0.47) | METAP2METAP1MMEACECPA1 | |
| SCHEMBL1418768 | 0.77 | CYP2C19 (0.47) | METAP2METAP1MMEACECPA1 | |
| SCHEMBL10955566 | 0.77 | TSHR (0.46) | KMT2APYGL | |
| SCHEMBL4062734 | 0.76 | LMNA (0.41) | KMT2A | |
| SCHEMBL24977466 | 0.75 | KMT2A (0.41) | KMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL2649397 | 0.74 | MMP2 (0.46) | ACP3METAP2METAP1KMT2AMME | |
| SCHEMBL18496743 | 0.74 | POLB (0.47) | KMT2AL3MBTL1 | |
| SCHEMBL20563859 | 0.73 | CYP1A2 (0.55) | KMT2ACYSLTR2CYSLTR1CPA1L3MBTL1 | |
| SCHEMBL8425190 | 0.73 | ALDH1A1 (0.38) | KMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL2648458 | 0.72 | MME (0.50) | METAP2METAP1KMT2ACTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492940-B1 | Process for producing and purifying 3,4-dihydrocoumarin | SUMITOMO CHEMICAL CO (JP) | 1995-07-12 | — | — | EP | claimed |
| US-5218129-A | Cyclization, dehydrogenation of a 3-(2-cyclohexanoyl)propionic ester | SUMITOMO CHEMICAL CO., LTD. (JP) | 1993-06-08 | — | — | US | claimed |
| EP-0492940-A1 | Process for producing and purifying 3,4-dihydrocoumarin | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1992-07-01 | — | — | EP | claimed |