Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | NPY2R | P49146 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479830 | 0.89 | ALDH1A1 (0.48) | ALDH1A1LMNANPY1RNPY2RL3MBTL1 | |
| SCHEMBL28476003 | 0.85 | LMNA (0.45) | ALDH1A1LMNANPY1RNPY2RL3MBTL1 | |
| SCHEMBL8990014 | 0.77 | HTT (0.42) | ALDH1A1LMNANPY1RNPY2RL3MBTL1 | |
| SCHEMBL28476340 | 0.77 | CHRM4 (0.43) | ALDH1A1LMNANPY1RNPY2RL3MBTL1 | |
| Water SCHEMBL11318555 | 0.77 | GSR (0.45) | ALDH1A1LMNANPY1RNPY2RL3MBTL1 | |
| SCHEMBL16444526 | 0.74 | MAPK1 (0.54) | ALDH1A1L3MBTL1MAPK1HTTCHRM4 | |
| SCHEMBL9283479 | 0.74 | ALDH1A1 (0.40) | ALDH1A1LMNANPY1RNPY2RL3MBTL1 | |
| SCHEMBL9285780 | 0.73 | ALDH1A1 (0.40) | ALDH1A1LMNANPY1RNPY2RL3MBTL1 | |
| SCHEMBL8021385 | 0.73 | MAPT (0.59) | ALDH1A1LMNAL3MBTL1MAPK1HTT | |
| SCHEMBL7478340 | 0.72 | ALDH1A1 (0.40) | ALDH1A1LMNANPY1RNPY2RL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030659-A1 | BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINERGIC AGENTS, ESP. SELECTIVE FOR THE DOPAMINE D3 RECEPTOR | WARNER-LAMBERT COMPANY (US) | 1995-11-16 | — | — | WO | disclosed |