Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485545 | 0.93 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL7473993 | 0.89 | ADORA3 (0.41) | ALDH1A1SMN1; SMN2KDM4EHSD17B10TLR7 | |
| SCHEMBL7478966 | 0.81 | HSD17B10 (0.43) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL7486557 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL8046841 | 0.78 | LTA4H (0.47) | LMNATSHRKDM4EHSD17B10HPGD | |
| SCHEMBL7476196 | 0.77 | KDM4E (0.40) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL7481507 | 0.76 | KDM4E (0.53) | ALDH1A1SMN1; SMN2TSHRKDM4EHSD17B10 | |
| SCHEMBL8034969 | 0.73 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2LMNATSHRNPSR1 | |
| SCHEMBL9285258 | 0.72 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL8044065 | 0.72 | HSD17B10 (0.47) | ALDH1A1SMN1; SMN2LMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-B1 | PROTON PUMP INHIBITOR | APOTEX INC (CA) | 2002-05-15 | — | — | EP | disclosed |
| US-6114537-A | 1,2,4-THIADIAZOLE COMPOUND IS USEFUL FOR TRAPPING THIOL COMPOUNDS AND SELECTIVELY CHANGING THIOLS TO DISULFIDE COMPOUNDS | APOTEX INC. (CA) | 2000-09-05 | — | — | US | disclosed |
| US-6093738-A | IMIDAZO(1,2-D)-THIADIAZOLE COMPOUNDS; PEPTIC ULCER TREATMENT | KARIMIAN KHASHAYAR (CA) | 2000-07-25 | — | — | US | disclosed |