Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | AHCY | P23526 | 9/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378379 | 0.81 | AHCY (0.66) | FGFR1SLC22A6AHCYCYP3A4ENPP1 | |
| SCHEMBL1733016 | 0.81 | AHCY (0.66) | FGFR1SLC22A6AHCYCYP3A4ENPP1 | |
| SCHEMBL1733018 | 0.81 | AHCY (0.66) | FGFR1SLC22A6AHCYCYP3A4ENPP1 | |
| Butane SCHEMBL1731733 | 0.77 | AHCY (0.60) | FGFR1SLC22A6AHCYCYP3A4ENPP1 | |
| Adefovir SCHEMBL29365535 | 0.77 | FGFR1 (1.00) | FGFR1SLC22A6CYP3A4ENPP1ADORA2A | |
| Adefovir SCHEMBL49373 | 0.77 | FGFR1 (1.00) | FGFR1SLC22A6CYP3A4ENPP1ADORA2A | |
| SCHEMBL28742775 | 0.76 | FGFR1 (0.65) | FGFR1SLC22A6AHCYCYP3A4ENPP1 | |
| SCHEMBL6158904 | 0.76 | AHCY (0.76) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9563488 | 0.76 | AHCY (0.60) | FGFR1SLC22A6AHCYCYP3A4ENPP1 | |
| SCHEMBL9563483 | 0.76 | AHCY (0.60) | FGFR1SLC22A6AHCYCYP3A4ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0631583-A1 | ANTIVIRAL PHOSPHONIC ACID DERIVATIVES OF PURINE ANALOGUES | SMITHKLINE BEECHAM PLC (GB) | 1995-01-04 | — | — | EP | disclosed |
| WO-1993019075-A1 | ANTIVIRAL PHOSPHONIC ACID DERIVATIVES OF PURINE ANALOGUES | SMITHKLINE BEECHAM PLC (GB) | 1993-09-30 | — | — | WO | disclosed |
| WO-1992009611-A1 | PHARMACEUTICALS | BEECHAM GROUP PLC (GB) | 1992-06-11 | — | — | WO | disclosed |