Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 9/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | PI4KA | P42356 | 2/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563488 | 1.00 | AHCY (0.60) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1733016 | 0.78 | AHCY (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1733018 | 0.78 | AHCY (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL11378379 | 0.78 | AHCY (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9563486 | 0.78 | AHCY (0.55) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL6158904 | 0.76 | AHCY (0.76) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9285391 | 0.76 | FGFR1 (0.62) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL11307115 | 0.76 | AHCY (0.63) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| Butane SCHEMBL1731733 | 0.74 | AHCY (0.60) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL28742775 | 0.74 | FGFR1 (0.65) | AHCYADORA2AADORA1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531597-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |