Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285951 | 1.00 | CYP3A4 (0.42) | CYP3A4CYP2D6CYP2C19L3MBTL1GAA | |
| SCHEMBL9258457 | 0.83 | LMNA (0.50) | CYP3A4CYP2D6CYP2C19L3MBTL1GAA | |
| SCHEMBL7288615 | 0.82 | MMP8 (0.49) | CYP3A4CYP2D6CYP2C19L3MBTL1GAA | |
| SCHEMBL3067053 | 0.79 | EPHX1 (0.49) | CYP3A4CYP2D6CYP2C19GAATDP1 | |
| SCHEMBL29029672 | 0.79 | SMN1; SMN2 (0.48) | L3MBTL1TDP1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL28633131 | 0.77 | SMN1; SMN2 (0.51) | CYP3A4CYP2D6CYP2C19SMN1; SMN2MEN1 | |
| SCHEMBL29029675 | 0.75 | SMN1; SMN2 (0.44) | L3MBTL1TDP1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL9366743 | 0.75 | LMNA (0.47) | TDP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL2512047 | 0.74 | CYP3A4 (0.49) | CYP3A4CYP2D6CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL29069352 | 0.74 | ALDH1A1 (0.52) | CYP3A4CYP2D6CYP2C19SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995023135-A1 | DIPHENYL-2-PIPERIDINONE AND -2-PYRROLIDINONE DERIVATIVES HAVING ANTI-CONVULSANT AND NEUROPROTECTIVE ACTIVITY | FISONS CORPORATION (US) | 1995-08-31 | — | — | WO | disclosed |