SCHEMBL9286355

SCHEMBL9286355

CC[C@H](N)C(NCC(C)C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.42
ANPEP P15144 1/20 0.40
TAAR1 Q96RJ0 4/20 0.38
LMNA P02545 3/20 0.37
APAF1 O14727 1/20 0.37
ADRA2A P08913 2/20 0.36
ADRA2C P18825 1/20 0.36
HIF1A Q16665 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 2/20 0.36
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CHRM1 P11229 1/20 0.36
SMPD1 P17405 1/20 0.36
DRD1 P21728 1/20 0.36
TBXA2R P21731 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8669293 0.98 TAAR1 (0.41) AOC3ANPEPTAAR1LMNAAPAF1
SCHEMBL6894924 0.78 KDM4E (0.43) AOC3ANPEPLMNAAPAF1ADRA2A
SCHEMBL29433956 0.75 AOC3 (0.53) AOC3LMNAAPAF1ADRA2AADRA2C
SCHEMBL6143595 0.74 LMNA (0.42) AOC3TAAR1LMNAAPAF1ADRA2A
SCHEMBL5227140 0.71 APAF1 (0.63) AOC3ANPEPTAAR1LMNAAPAF1
SCHEMBL26217022 0.71 APAF1 (0.63) AOC3ANPEPTAAR1LMNAAPAF1
SCHEMBL5228652 0.71 APAF1 (0.63) AOC3ANPEPTAAR1LMNAAPAF1
SCHEMBL10159454 0.71 TAAR1 (0.46) AOC3TAAR1LMNAADRA2AADRA2C
SCHEMBL21799526 0.69 TAAR1 (0.50) AOC3ANPEPTAAR1LMNAAPAF1
SCHEMBL26923438 0.69 TACR1 (0.50) TAAR1LMNAADRA2AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995006030-A1 HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1995-03-02 WO disclosed