Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.34 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784777 | 0.75 | NPC1 (0.51) | NPC1RAB9AALDH1A1SLC18A3MEN1 | |
| SCHEMBL6785452 | 0.74 | RXFP1 (0.44) | APEX1MYCNPC1RAB9AHDAC6 | |
| SCHEMBL8152134 | 0.74 | RXFP1 (0.44) | APEX1MYCNPC1RAB9AUHRF1 | |
| SCHEMBL6784074 | 0.73 | KDM4E (0.42) | APEX1MYCNPC1RAB9AUHRF1 | |
| SCHEMBL10967773 | 0.71 | ADRA2A (0.46) | NPC1RAB9AALDH1A1POLBKMT2A | |
| SCHEMBL6610930 | 0.70 | NPC1 (0.40) | APEX1NPC1RAB9AHDAC1HDAC2 | |
| SCHEMBL8807579 | 0.69 | UHRF1 (0.35) | APEX1MYCNPC1RAB9AUHRF1 | |
| SCHEMBL8807587 | 0.69 | UHRF1 (0.35) | APEX1MYCNPC1RAB9AHDAC6 | |
| SCHEMBL9535798 | 0.66 | ALDH1A1 (0.38) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL8810234 | 0.66 | POLB (0.34) | APEX1MYCHDAC6UHRF1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664807-A1 | QUINOXALINEDIONE DERIVATIVES AS EAA ANTAGONISTS. | WARNER LAMBERT CO (US) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994009000-A1 | QUINOXALINEDIONE DERIVATIVES AS EAA ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1994-04-28 | — | — | WO | disclosed |