Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782509 | 0.88 | RAB9A (0.32) | EPHX2POLB | |
| SCHEMBL782506 | 0.85 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL782434 | 0.85 | LMNA (0.32) | TSHRL3MBTL1 | |
| SCHEMBL769209 | 0.83 | MEN1 (0.37) | ALDH1A1MEN1MAPK1KMT2AL3MBTL1 | |
| SCHEMBL782638 | 0.83 | OPRM1 (0.30) | — | |
| SCHEMBL782276 | 0.82 | HDAC3 (0.35) | EPHX2MEN1MAPK1KMT2AL3MBTL1 | |
| SCHEMBL12071075 | 0.82 | EPHX2 (0.36) | EPHX2POLBTSHRALDH1A1MAPT | |
| SCHEMBL769203 | 0.82 | MEN1 (0.32) | EPHX2MEN1MAPK1KMT2A | |
| SCHEMBL46135 | 0.81 | EPHX2 (0.35) | EPHX2POLBTSHRALDH1A1 | |
| SCHEMBL782328 | 0.81 | KCNH2 (0.33) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069008-A1 | 3-SUBSTITUTED SPIROHETEROCYCLIC FURAN AND THIOFURAN DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |