Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | HEXA | P06865 | 3/20 | 0.39 |
| ▸ | HEXB | P07686 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12561279 | 0.89 | KEAP1 (0.49) | KEAP1NFE2L2TLR9ALDH1A1HPGD | |
| SCHEMBL9290301 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL7129339 | 0.82 | HPGD (0.65) | KEAP1NFE2L2TLR9ALDH1A1HPGD | |
| SCHEMBL9290305 | 0.78 | HPGD (0.43) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL6272260 | 0.77 | KEAP1 (0.65) | KEAP1NFE2L2TLR9ALDH1A1HPGD | |
| SCHEMBL9290371 | 0.74 | ALDH1A1 (0.61) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL21558556 | 0.73 | MPO (0.44) | KEAP1NFE2L2ALDH1A1HPGDCYP1B1 | |
| SCHEMBL9290429 | 0.72 | KMT2A (0.44) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL12561280 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL9290293 | 0.70 | PDE6D (0.55) | KEAP1NFE2L2ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2458941-A1 | OPTICAL FILTER | Adeka Corporation (JP) | 2012-05-30 | — | — | EP | disclosed |