SCHEMBL9290296

SCHEMBL9290296

C=Cc1cccc(N2C(=O)c3cccc4c(C(C)(C)C)ccc2c34)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.38
MEN1 O00255 7/20 0.38
USP2 O75604 7/20 0.38
KEAP1 Q14145 4/20 0.38
NFE2L2 Q16236 4/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
ALDH1A1 P00352 6/20 0.37
HTT P42858 4/20 0.37
TNNI3 P19429 2/20 0.37
TNNT2 P45379 2/20 0.37
TNNC1 P63316 2/20 0.37
TLR9 Q9NR96 1/20 0.37
RORC P51449 2/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KDM4E B2RXH2 4/20 0.34
MAPT P10636 4/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
PDE6D O43924 1/20 0.33
NR1H2 P55055 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9290292 0.83 ALDH1A1 (0.49) KMT2AMEN1USP2KEAP1NFE2L2
SCHEMBL9290374 0.81 PDE6D (0.44) KMT2AMEN1USP2KEAP1NFE2L2
SCHEMBL12561361 0.80 KMT2A (0.44) KMT2AMEN1USP2KEAP1NFE2L2
SCHEMBL9290304 0.80 MEN1 (0.44) KMT2AMEN1USP2KEAP1NFE2L2
SCHEMBL9290436 0.78 KMT2A (0.42) KMT2AMEN1USP2KEAP1NFE2L2
SCHEMBL9290455 0.78 NR1H3 (0.37) KMT2AMEN1USP2KEAP1NFE2L2
SCHEMBL9290295 0.75 KMT2A (0.48) KMT2AMEN1ALDH1A1HTTTLR9
SCHEMBL9290299 0.75 PDE6D (0.40) KMT2AMEN1USP2KEAP1NFE2L2
SCHEMBL9290347 0.75 PDE6D (0.39) KMT2AMEN1USP2KEAP1NFE2L2
SCHEMBL9290353 0.75 PDE6D (0.39) KMT2AMEN1USP2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152538-A1 OPTICAL FILTER C1R, CBR3, CBR1 KMT2A 4130/4885MEN1 3537/4885USP2 3865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.