Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291348 | 0.86 | NPC1 (0.48) | POLBNPC1RAB9AKDM4EHPGD | |
| SCHEMBL9291454 | 0.84 | NPC1 (0.48) | POLBNPC1RAB9AKDM4EHPGD | |
| SCHEMBL9324363 | 0.83 | RAB9A (0.54) | POLBNPC1RAB9AKDM4EHPGD | |
| SCHEMBL9408778 | 0.82 | NPC1 (0.56) | POLBNPC1RAB9AKDM4EHPGD | |
| SCHEMBL9408745 | 0.81 | NPC1 (0.54) | POLBNPC1RAB9AKDM4EHPGD | |
| SCHEMBL9291406 | 0.81 | POLB (0.43) | POLBNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL8043991 | 0.79 | NPC1 (0.52) | POLBNPC1RAB9AKDM4EHPGD | |
| SCHEMBL9408879 | 0.79 | NPC1 (0.52) | POLBNPC1RAB9AKDM4EHPGD | |
| SCHEMBL9408822 | 0.79 | RAB9A (0.52) | POLBNPC1RAB9AKDM4EHPGD | |
| SCHEMBL6530775 | 0.78 | NPC1 (0.51) | POLBNPC1RAB9AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319090-A | Benzotriazole and oxanilide UV absorber hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-06-07 | — | — | US | disclosed |
| US-5233047-A | Benzotriazole UV absorber hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1993-08-03 | — | — | US | disclosed |