Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11186607 | 0.91 | OPRM1 (0.51) | NAAAOPRM1HTTALDH1A1 | |
| SCHEMBL10639479 | 0.91 | OPRM1 (0.51) | NAAALMNAOPRM1CTSKNPC1 | |
| SCHEMBL9828137 | 0.88 | HTT (0.56) | LMNAOPRM1HTTKMT2AALDH1A1 | |
| SCHEMBL21798492 | 0.85 | EPHX2 (0.60) | KMT2AALDH1A1CNR1CNR2NPC1 | |
| SCHEMBL9828186 | 0.84 | HTT (0.52) | NAAALMNAOPRM1HTTKMT2A | |
| SCHEMBL10638831 | 0.84 | OPRM1 (0.53) | NAAAOPRM1CTSKKMT2AMEN1 | |
| SCHEMBL9831112 | 0.83 | OPRM1 (0.50) | OPRM1TSHRHTT | |
| SCHEMBL9293279 | 0.83 | OPRM1 (0.50) | NAAAOPRM1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL17550883 | 0.83 | OPRM1 (0.50) | NAAALMNAOPRM1 | |
| Hydrochloric Acid SCHEMBL28345934 | 0.82 | OPRM1 (0.49) | NAAAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284958-A | Acylation, cyclization of a 5-hydrazine-1H-pyrazole | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-08 | — | — | US | disclosed |
| US-5214149-A | Process for producing a 1H-pyrazolo[5,1-c]-1,2,4-triazole compound | FUJI PHOTO FILM CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |