Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956153 | 0.76 | CYP19A1 (0.42) | CYP19A1FAAHMGLLL3MBTL3L3MBTL1 | |
| SCHEMBL18577951 | 0.73 | OGA (0.42) | L3MBTL3L3MBTL1OPRM1CHRM2CHRM4 | |
| SCHEMBL21640161 | 0.73 | OPRL1 (0.39) | CYP19A1L3MBTL3L3MBTL1OPRM1CHRM2 | |
| SCHEMBL8438434 | 0.72 | CYP19A1 (0.51) | CYP19A1FAAHMGLLCYP26A1L3MBTL3 | |
| SCHEMBL9293015 | 0.72 | CYP19A1 (0.51) | CYP19A1FAAHMGLLL3MBTL3L3MBTL1 | |
| SCHEMBL18556116 | 0.71 | OPRM1 (0.40) | L3MBTL3L3MBTL1OPRM1CHRM2CHRM4 | |
| SCHEMBL21641112 | 0.70 | OGA (0.41) | L3MBTL3L3MBTL1OPRM1MEN1KMT2A | |
| SCHEMBL18765288 | 0.70 | OPRD1 (0.44) | ACHEMEN1KMT2A | |
| SCHEMBL4955461 | 0.69 | L3MBTL1 (0.40) | CYP19A1FAAHMGLLL3MBTL3L3MBTL1 | |
| SCHEMBL13292485 | 0.69 | CYP19A1 (1.00) | CYP19A1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342846-A | 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents | SYNPHAR LABORATORIES, INC. (CA) | 1994-08-30 | — | — | US | disclosed |
| WO-1993024481-A1 | 7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS AND RELATED COMPOUNDS AS ANTIBACTERIAL AGENTS | SYNPHAR LABORATORIES, INC. (CA) | 1993-12-09 | — | — | WO | disclosed |
| EP-0561850-A1 | 7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | SYNPHAR LABORATORIES INC. (CA) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010492-A1 | 7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | SYNPHAR LABORATORIES, INC. (CA) | 1992-06-25 | — | — | WO | disclosed |