Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 14/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296349 | 1.00 | LTB4R2 (0.33) | LTB4R2AGTR1AGTR2ABCB11GP6 | |
| SCHEMBL9296496 | 0.90 | AGTR1 (0.33) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL9296491 | 0.90 | AGTR1 (0.33) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL9296082 | 0.73 | AGT (0.41) | AGTR1AGTR2 | |
| SCHEMBL9296077 | 0.73 | AGT (0.41) | AGTR1AGTR2 | |
| SCHEMBL16403650 | 0.71 | LTB4R2 (0.35) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL6953051 | 0.69 | HSD11B1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9709753 | 0.69 | LTB4R2 (0.42) | LTB4R2AGTR1AGTR2ABCB11GP6 | |
| SCHEMBL9709732 | 0.68 | LTB4R2 (0.41) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL6949197 | 0.68 | HSD11B1 (0.47) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326776-A | Tetrazoles | ABBOTT LABORATORIES (US) | 1994-07-05 | — | — | US | disclosed |