Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27546882 | 0.81 | HCAR2 (0.32) | POLBKDM4E | |
| SCHEMBL3750452 | 0.68 | ATM (0.43) | POLBALDH1A1HDAC4 | |
| SCHEMBL28445883 | 0.67 | MAOA (0.33) | — | |
| SCHEMBL30931450 | 0.67 | POLB (0.38) | POLBKDM4EALDH1A1EDNRAHDAC4 | |
| SCHEMBL18921545 | 0.64 | CYP2D6 (0.41) | POLBKDM4EALDH1A1EDNRAEDNRB | |
| SCHEMBL23513879 | 0.64 | EDNRA (0.32) | ALDH1A1EDNRA | |
| SCHEMBL4607072 | 0.64 | SLC6A2 (0.40) | POLBEDNRAPTGDR2 | |
| SCHEMBL7596802 | 0.64 | POLB (0.52) | POLBEDNRAHDAC4EDNRB | |
| SCHEMBL28044427 | 0.63 | HTR2A (0.31) | — | |
| SCHEMBL27300866 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629211-A1 | 4-OXO-2 THIOXOIMIDAZOLIDINE DERIVATES AS INHIBITORS OF BLOOD PLATELET AGGREGATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-21 | — | — | EP | disclosed |
| WO-1993018057-A1 | 4-OXO-2 THIOXOIMIDAZOLIDINE DERIVATES AS INHIBITORS OF BLOOD PLATELET AGGREGATION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1993-09-16 | — | — | WO | disclosed |
| EP-0115345-A1 | Process for the resolution of racemic optically active bicyclic imino-alpha-carboxylic acid esters and use of the compounds obtainable in this way for the synthesis of carboxyalkyl dipeptides | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-08 | — | — | EP | disclosed |