Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | VDR | P11473 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298632 | 1.00 | ALOX12 (0.57) | ALOX12HPGDL3MBTL1CA1MEN1 | |
| SCHEMBL7574185 | 0.94 | HPGD (0.57) | ALOX12HPGDL3MBTL1CA1MEN1 | |
| SCHEMBL11301777 | 0.85 | CA12 (0.45) | ALOX12L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL7582132 | 0.84 | ALDH1A1 (0.57) | L3MBTL1CA1MEN1KMT2ANPC1 | |
| SCHEMBL7584383 | 0.83 | ALOX5 (0.50) | ALOX12HPGDL3MBTL1CA1MEN1 | |
| SCHEMBL2483519 | 0.81 | FPR2 (0.49) | CA1POLBALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL2483521 | 0.81 | FPR2 (0.49) | CA1POLBALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL146704 | 0.81 | FPR2 (0.49) | CA1POLBALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL8151157 | 0.80 | ALOX12 (0.65) | ALOX12HPGDL3MBTL1CA1MEN1 | |
| SCHEMBL28534876 | 0.79 | FPR2 (0.47) | CA1KMT2APOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374656-A | Nervous system disorders, gastrointestinal disorders | RHONE-POULENC RORER, S.A. (FR) | 1994-12-20 | — | — | US | disclosed |