Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029475 | 0.92 | RAB9A (0.50) | RAB9ASMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL10828058 | 0.83 | PSMB8 (0.49) | PSMB8MAPTTDP1MEN1KMT2A | |
| SCHEMBL9299696 | 0.83 | RAB9A (0.55) | RAB9ASMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL9332317 | 0.82 | PSMB8 (0.48) | PSMB8 | |
| SCHEMBL8942532 | 0.77 | LMNA (0.60) | RAB9ASMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL11360493 | 0.76 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL10828057 | 0.74 | FFAR1 (0.42) | PSMB8HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL9299682 | 0.74 | RAB9A (0.55) | RAB9ASMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL10959419 | 0.73 | DGAT1 (0.60) | PSMB8MAPT | |
| SCHEMBL9332308 | 0.73 | PSMB8 (0.40) | PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376657-A | Fungicides | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |