Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 10/20 | 0.40 |
| ▸ | TEK | Q02763 | 9/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332308 | 0.91 | PSMB8 (0.40) | PSMB8KDRTEKDGAT1SOAT1 | |
| SCHEMBL9335261 | 0.85 | KDM4E (0.44) | KDRTEKRAF1CHEK2 | |
| SCHEMBL9331777 | 0.84 | MAPT (0.45) | KDRTEKRAF1CHEK2 | |
| SCHEMBL10828058 | 0.83 | PSMB8 (0.49) | PSMB8KDRTEKDGAT1SOAT1 | |
| SCHEMBL9298987 | 0.82 | RAB9A (0.50) | PSMB8 | |
| SCHEMBL8825678 | 0.77 | NPBWR1 (0.33) | KDRTEK | |
| SCHEMBL9332220 | 0.77 | AR (0.31) | — | |
| SCHEMBL9335269 | 0.76 | NPSR1 (0.40) | KDRRAF1BRAF | |
| SCHEMBL27348469 | 0.76 | RAB9A (0.33) | KDRTEKBRAF | |
| SCHEMBL11041547 | 0.76 | KIF11 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448206-B1 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LTD (GB) | 1994-12-28 | — | — | EP | disclosed |
| US-5306692-A | Herbicidal indazole and benzimidazole compounds | ZENECA LIMITED (GB) | 1994-04-26 | — | — | US | disclosed |