Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5057415 | 0.91 | ALDH1A1 (0.46) | MAPTALDH1A1CA12CA1CA2 | |
| SCHEMBL27468651 | 0.83 | CA1 (0.57) | MAPTHPGDALDH1A1LMNAHSD17B1 | |
| SCHEMBL9300725 | 0.83 | TDP1 (0.57) | MAPTHPGDRAB9AALDH1A1KMT2A | |
| Butane SCHEMBL7720074 | 0.83 | TDP1 (0.41) | MAPTHPGDALDH1A1CA12CA1 | |
| SCHEMBL4910303 | 0.83 | CA1 (0.57) | MAPTRAB9AALDH1A1STSL3MBTL1 | |
| SCHEMBL21679928 | 0.82 | MAPT (0.54) | MAPTHPGDRAB9AALDH1A1STS | |
| SCHEMBL4910445 | 0.82 | CA1 (0.59) | MAPTRAB9ASMN1; SMN2NPC1CA1 | |
| SCHEMBL2576355 | 0.82 | RAB9A (0.47) | MAPTHPGDRAB9AALDH1A1KMT2A | |
| SCHEMBL20013249 | 0.82 | LMNA (0.44) | MAPTHPGDRAB9AALDH1A1KMT2A | |
| SCHEMBL191087 | 0.82 | HPGD (0.48) | MAPTHPGDRAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352820-A | Expedient route to aryl propenoic esters | AMERICAN CYANAMID COMPANY | 1994-10-04 | — | — | US | claimed |
| US-5352820-A | Expedient route to aryl propenoic esters | AMERICAN CYANAMID COMPANY | 1994-10-04 | — | — | US | disclosed |