Methacrylic Acid

Methacrylic Acid

SCHEMBL9299147

C=C(C)C(=O)O.C=C(C)C(=O)O.C=Cc1ccncc1.OCCO

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JUN P05412 1/20 0.38
NFKB1 P19838 1/20 0.38
SNCA P37840 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
PTGS2 P35354 1/20 0.35
NAPRT Q6XQN6 1/20 0.34
CYP1A2 P05177 3/20 0.34
CYP2C19 P33261 3/20 0.34
ALDH1A1 P00352 3/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
TSHR P16473 2/20 0.33
KDM1A O60341 1/20 0.33
HTT P42858 1/20 0.33
PLOD2 O00469 1/20 0.33
PLOD3 O60568 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL16669353 0.93 JUN (0.42) JUNNFKB1SNCASMN1; SMN2PTGS2
Methacrylic Acid SCHEMBL17187723 0.91 JUN (0.41) JUNNFKB1SNCASMN1; SMN2PTGS2
Styrene SCHEMBL3446819 0.84 ALDH1A1 (0.52) PTGS2ALDH1A1CYP3A4CYP2C9TSHR
Styrene SCHEMBL27543907 0.84 ALDH1A1 (0.52) PTGS2ALDH1A1CYP3A4CYP2C9TSHR
Styrene SCHEMBL3007716 0.84 ALDH1A1 (0.52) PTGS2ALDH1A1CYP3A4CYP2C9TSHR
Acetic Acid SCHEMBL8516899 0.84 JUN (0.47) JUNNFKB1SNCASMN1; SMN2PTGS2
Ethylene Glycol SCHEMBL8742258 0.84 ALDH1A1 (0.46) JUNNFKB1SNCASMN1; SMN2CYP1A2
SCHEMBL15637663 0.81 TBXAS1 (0.35) JUNNFKB1SNCASMN1; SMN2PTGS2
SCHEMBL6024939 0.81 SNCA (0.40) JUNNFKB1SNCASMN1; SMN2CYP1A2
SCHEMBL4407600 0.81 TBXAS1 (0.35) JUNNFKB1SNCASMN1; SMN2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112513162-A Novel compositions for bittering agents UPL有限公司 2021-03-16 CN claimed
US-5316774-A Controlled release of drugs in intestines with enteric material and entrainment in polymers ADVANCED POLYMER SYSTEMS, INC. (US) 1994-05-31 US claimed
CN-112513162-A Novel compositions for bittering agents UPL有限公司 2021-03-16 CN disclosed
EP-3431177-B1 VINYLPYRIDINE RESIN FOR CATALYST CARRIERS, PRODUCTION METHOD THEREFOR, AND CATALYST FOR METHANOL CARBONYLATION REACTION CHIYODA CORP (JP) 2020-10-28 EP disclosed