Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31612942 | 0.89 | LMNA (0.56) | NPC1RAB9ANOTUMALDH1A1CYP3A4 | |
| SCHEMBL13674387 | 0.88 | NPC1 (0.55) | NPC1RAB9ANOTUMALDH1A1CYP3A4 | |
| SCHEMBL22280547 | 0.84 | ESR2 (0.65) | NPC1RAB9ANOTUMMAPK1KMT2A | |
| SCHEMBL7622171 | 0.84 | ESR2 (0.65) | NPC1RAB9ACYP3A4MAPK1KMT2A | |
| SCHEMBL13030444 | 0.84 | NPC1 (0.77) | NPC1RAB9ANOTUMALDH1A1CYP3A4 | |
| SCHEMBL29950410 | 0.84 | ALDH1A1 (0.61) | NPC1RAB9AALDH1A1CYP3A4MAPK1 | |
| SCHEMBL67498 | 0.84 | ALDH1A1 (0.61) | NPC1RAB9AALDH1A1CYP3A4MAPK1 | |
| Formaldehyde SCHEMBL27994586 | 0.84 | HPGD (0.56) | NPC1RAB9ANOTUMALDH1A1CYP3A4 | |
| SCHEMBL11192923 | 0.83 | BACE1 (0.66) | NPC1RAB9AALDH1A1CYP3A4MAPK1 | |
| SCHEMBL6011542 | 0.82 | ALDH1A1 (0.55) | NPC1RAB9ANOTUMALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015530-A | Urolithin derivatives and methods of use thereof | 范徳利亚股份公司 | 2023-11-07 | — | — | CN | disclosed |
| EP-2271651-B1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-01-01 | — | — | EP | disclosed |
| EP-2346887-B1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2013-12-25 | — | — | EP | disclosed |
| US-8546600-B2 | Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite | DOW TECHNOLOGY INVESTMENTS LLC | 2013-10-01 | — | — | US | disclosed |
| EP-2257560-B1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | UNION CARBIDE CHEM PLASTIC (US) | 2013-07-17 | — | — | EP | disclosed |
| US-8471066-B2 | Slurry process for phosphoromonochloridite synthesis | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC | 2013-06-25 | — | — | US | disclosed |
| US-8097749-B2 | Isothermal process for phosphoromonochloridite synthesis | Union Carbide Chemical and Plastics Technology Technology | 2012-01-17 | — | — | US | disclosed |
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | DOW TECHNOLOGY INVESTMENTS LLC | 2011-08-11 | — | — | US | disclosed |
| EP-2346887-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | Dow Technology Investments LLC (US) | 2011-07-27 | — | — | EP | disclosed |
| US-20110021840-A1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYTHESIS | UNION CARBIDE CORPORATION | 2011-01-27 | — | — | US | disclosed |
| EP-2271651-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | Dow Global Technologies Inc. (US) | 2011-01-12 | — | — | EP | disclosed |
| EP-2257560-A1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | Union Carbide Chemicals & Plastics Technology Llc (Formerly Union Carbide Chemicals & Plastics Technology Corporation) (US) | 2010-12-08 | — | — | EP | disclosed |
| WO-2010042313-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2010-04-15 | — | — | WO | disclosed |
| US-20090247790-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | UNION CARBIDE CORPORATION | 2009-10-01 | — | — | US | disclosed |
| WO-2009120210-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-10-01 | — | — | WO | disclosed |
| WO-2009120529-A1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (FORMERLY UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION) (US) | 2009-10-01 | — | — | WO | disclosed |
| EP-0590613-B1 | Improved hydroformylation process | UNION CARBIDE CHEM PLASTIC (US) | 1997-01-08 | — | — | EP | disclosed |
| EP-0590613-A2 | Improved hydroformylation process | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1994-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247790-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | PIM3, PLCB3, PLCD1 | NPC1 4133/4885RAB9A 4694/4885NOTUM 936/4885 |
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | SOST, PLCB3, PPIP5K2 | NPC1 3196/4885RAB9A 3429/4885NOTUM 2434/4885 |
| US-20110021840-A1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYTHESIS | PSPH, SPIN3, SYNGR2 | NPC1 3610/4885RAB9A 4031/4885NOTUM 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.