Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299671 | 0.81 | KMT2A (0.49) | KMT2AHTTGAAMEN1CA2 | |
| SCHEMBL894793 | 0.80 | KMT2A (0.57) | PKMKMT2AHTTGAAMEN1 | |
| SCHEMBL9299573 | 0.78 | PKM (0.52) | PKMKMT2AHTTGAAMEN1 | |
| SCHEMBL28456751 | 0.77 | KDM4E (0.50) | PKMKMT2AHTTGAAMEN1 | |
| SCHEMBL6553024 | 0.76 | PKM (0.75) | PKMKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL6534914 | 0.74 | KMT2A (0.57) | KMT2AHTTGAAMEN1CA2 | |
| SCHEMBL29596265 | 0.72 | ALDH1A1 (0.69) | PKMKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL12100862 | 0.72 | ALDH1A1 (0.69) | PKMKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL8605670 | 0.72 | ALDH1A1 (0.69) | PKMKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL5461742 | 0.71 | LMNA (0.65) | PKMKMT2AHTTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280027-A | Quinazoline containing compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-18 | — | — | US | disclosed |