Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447555 | 0.84 | KDM4E (0.57) | KDM4ETDP1ALDH1A1LMNAHTT | |
| SCHEMBL20916443 | 0.79 | CA12 (0.60) | KDM4ETDP1ALDH1A1HTTNFE2L2 | |
| SCHEMBL9299570 | 0.77 | PKM (0.52) | ALDH1A1LMNAHTTHPGDSMN1; SMN2 | |
| SCHEMBL28455376 | 0.77 | KDM4E (0.62) | KDM4ETDP1ALDH1A1LMNAHTT | |
| SCHEMBL30285113 | 0.75 | HTT (0.66) | KDM4ETDP1ALDH1A1LMNAHTT | |
| SCHEMBL27910100 | 0.73 | ALDH1A1 (0.67) | ALDH1A1LMNAHTTHPGDSMN1; SMN2 | |
| SCHEMBL8824675 | 0.73 | ALDH1A1 (0.56) | TDP1ALDH1A1LMNATSHRACHE | |
| SCHEMBL30883192 | 0.73 | TSHR (0.55) | TDP1ALDH1A1LMNAHTTTSHR | |
| SCHEMBL9299671 | 0.72 | KMT2A (0.49) | KDM4ETDP1ALDH1A1LMNAHTT | |
| SCHEMBL9703044 | 0.72 | LMNA (0.60) | ALDH1A1LMNAHTTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533694-B | Synthetic method of 2-imido hydantoin compound | 河南牧业经济学院 | 2023-03-14 | — | — | CN | disclosed |
| CN-111533694-A | Synthetic method of 2-imido hydantoin compound | 河南牧业经济学院 | 2020-08-14 | — | — | CN | disclosed |