Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299573 | 0.81 | PKM (0.52) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL2986907 | 0.80 | ALDH1A1 (0.67) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL13716196 | 0.78 | ALDH1A1 (0.54) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL4424908 | 0.77 | LMNA (0.48) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL9299671 | 0.76 | KMT2A (0.49) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL4432422 | 0.76 | MEN1 (0.58) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL4430321 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL2997455 | 0.74 | KMT2A (0.56) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL8514913 | 0.74 | MAPT (0.46) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL30780918 | 0.73 | TSHR (0.61) | ALDH1A1LMNATSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280027-A | Quinazoline containing compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-18 | — | — | US | disclosed |