Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7882856 | 0.88 | HPGD (0.43) | HPGDALDH1A1HDAC6MEN1KMT2A | |
| SCHEMBL7884002 | 0.85 | HPGD (0.49) | HPGDHDAC6MEN1KMT2AHDAC4 | |
| SCHEMBL847739 | 0.85 | HPGD (0.45) | PDK2HPGDALDH1A1HDAC6MEN1 | |
| SCHEMBL9299586 | 0.81 | HTR7 (0.47) | HPGDALDH1A1NAMPTHDAC4 | |
| SCHEMBL9300893 | 0.80 | HPGD (0.58) | HPGDTSHRHDAC6TP53MEN1 | |
| SCHEMBL14314804 | 0.78 | TSHR (0.55) | PDK2ALDH1A1TSHRL3MBTL1MEN1 | |
| SCHEMBL14233766 | 0.78 | ALDH1A1 (0.52) | PDK2HPGDALDH1A1NAMPTTSHR | |
| SCHEMBL849656 | 0.77 | HPGD (0.49) | PDK2HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL9299563 | 0.76 | HPGD (0.76) | HPGDALDH1A1TSHRL3MBTL1MEN1 | |
| SCHEMBL2228900 | 0.76 | HPGD (0.59) | PDK2HPGDALDH1A1NAMPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356893-A | Antidepressants, nervous system disorders | GLAXO GROUP LIMITED (GB) | 1994-10-18 | — | — | US | disclosed |
| EP-0533266-A1 | Benzanilide derivatives as 5-HT1D antagonists | GLAXO GROUP LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |