Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476513 | 0.85 | — | — | |
| SCHEMBL7208990 | 0.81 | ALDH1A1 (0.35) | CTSKTSHR | |
| SCHEMBL9300007 | 0.78 | TSHR (0.35) | CTSKCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL1476470 | 0.73 | SMPD1 (0.41) | TSHR | |
| SCHEMBL1470258 | 0.73 | CHRM1 (0.37) | CTSKCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL429578 | 0.72 | CA1 (0.35) | CTSKCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL7208961 | 0.72 | TSHR (0.42) | CTSKTSHR | |
| SCHEMBL7205871 | 0.71 | SMPD1 (0.44) | TSHR | |
| SCHEMBL1470150 | 0.71 | CHRM1 (0.36) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL5511319 | 0.70 | CTSK (0.34) | CTSKTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364691-A | Alk-1-enyloxy carbonates | ISP INVESTMENTS INC. (US) | 1994-11-15 | — | — | US | disclosed |
| US-5276174-A | Alk-1-enyloxy carbonates | ISP INVESTMENTS INC. (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0514482-A4 | VINYL ETHER COMPOUNDS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0514482-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991013052-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1991-09-05 | — | — | WO | disclosed |