Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.53 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300869 | 0.83 | FDPS (0.38) | FDPS | |
| SCHEMBL9302201 | 0.78 | FDPS (0.59) | FDPSCYP2C9CYP2C19MEN1ALDH1A1 | |
| SCHEMBL9302739 | 0.76 | FDPS (0.56) | FDPS | |
| SCHEMBL9300273 | 0.74 | FDPS (0.64) | FDPSCYP2C9CYP2C19MEN1ALDH1A1 | |
| SCHEMBL2203676 | 0.73 | FDPS (0.85) | FDPS | |
| SCHEMBL4473518 | 0.71 | LIPE (0.33) | LIPECYP2D6 | |
| SCHEMBL9303011 | 0.71 | FDPS (0.54) | FDPS | |
| SCHEMBL2472093 | 0.71 | FDPS (1.00) | FDPSMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| N-(Hexamethyleneimino)Methylenebisphosphonic Acid SCHEMBL12309768 | 0.71 | FDPS (1.00) | FDPSMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9301193 | 0.70 | FDPS (0.53) | FDPSCYP2C9CYP2C19MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350743-A | Treatment of osteoporosis | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0498424-A1 | Bisphosphonic acid derivatives and bone resorption inhibitors containing them | Kaken Pharmaceutical Co., Ltd. (JP) | 1992-08-12 | — | — | EP | disclosed |