SCHEMBL9300561

SCHEMBL9300561

Brc1ccc2ncsc2c1.Ic1ccc2scnc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KDM4E B2RXH2 1/20 0.41
HKDC1 Q2TB90 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
EGFR P00533 1/20 0.40
DYRK1A Q13627 1/20 0.39
GFER P55789 1/20 0.36
GPR183 P32249 1/20 0.36
KCNH2 Q12809 1/20 0.36
PTK6 Q13882 2/20 0.35
CCKBR P32239 1/20 0.35
RIPK2 O43353 2/20 0.34
RIPK3 Q9Y572 1/20 0.34
PFKFB3 Q16875 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31435454 0.85 ALDH1A1 (0.50) NPC1RAB9AALDH1A1HSD17B10KDM4E
SCHEMBL10543 0.85 NPC1 (0.54) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL14127237 0.85 NPC1 (0.54) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL928156 0.85 ALDH1A1 (0.50) NPC1RAB9AALDH1A1HSD17B10KDM4E
Hydrazine SCHEMBL27534766 0.81 NPC1 (0.51) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL858270 0.81 ALDH1A1 (0.50) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL927553 0.81 NPC1 (0.52) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL29457651 0.81 ALDH1A1 (0.50) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL9143839 0.78 RAB9A (0.44) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL11213454 0.69 RIPK3 (0.38) NPC1RAB9AMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5340694-A Containing hydrazine compound and cyanine dye; sensitivity, storage stability FUJI PHOTO FILM CO., LTD. (JP) 1994-08-23 US disclosed