Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127237 | 1.00 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2AKDM4E | |
| Hydrazine SCHEMBL27534766 | 0.96 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL9300561 | 0.85 | NPC1 (0.44) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL29457651 | 0.83 | ALDH1A1 (0.50) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL858270 | 0.83 | ALDH1A1 (0.50) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL9143839 | 0.81 | RAB9A (0.44) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL5178195 | 0.80 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL31214345 | 0.77 | DYRK1A (0.72) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL506591 | 0.75 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL23480172 | 0.74 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1067 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433072-B | Method for preparing aryl ketone by photocatalytic oxidation | 浙江工业大学 | 2023-08-08 | — | — | CN | claimed |
| CN-115504942-A | Synthesis method of alkyl or acyl substituted benzothiazole derivative | 汕头大学 | 2022-12-23 | — | — | CN | claimed |
| CN-115433072-A | Method for preparing aryl ketone by photocatalytic oxidation | 浙江工业大学 | 2022-12-06 | — | — | CN | claimed |
| EP-0271260-B1 | Supersensitization of silver halide emulsions | MINNESOTA MINING & MFG (US) | 1995-01-04 | — | — | EP | claimed |
| US-4873184-A | ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-10-10 | — | — | US | claimed |
| EP-0271260-A2 | Supersensitization of silver halide emulsions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-06-15 | — | — | EP | claimed |
| US-3970461-A | Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus | FUJI PHOTO FILM CO., LTD. (JA) | 1976-07-20 | — | — | US | claimed |
| CN-122036718-A | ALK5 inhibitor and preparation method and application thereof | 安炎达医药技术(广州)有限公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4724443-A1 | PYRAZOLO-PYRIMIDINONE COMPOUNDS FOR USE IN METHODS OF INHIBITING WEE1 A KINASE | Acrivon Therapeutics, Inc. (US) | 2026-04-15 | — | — | EP | disclosed |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2026-03-31 | — | — | US | disclosed |
| US-12570621-B2 | Short-acting 3,4-methylenedioxymethamphetamine (MDMA) analogs incorporating benzothiazole | APOAPSIS HOLDINGS, LLC (US) | 2026-03-10 | — | — | US | disclosed |
| US-12559485-B2 | CDK6/DYRK2 dual-target inhibitor, and preparation method therefor and use thereof | JIANGSU TASLY DIYI PHARMACEUTICAL CO. , LTD. (CN) | 2026-02-24 | — | — | US | disclosed |
| US-12534452-B2 | N-(1H-imidazol-2-yl)benzamide compound and pharmaceutical composition comprising the same as active ingredient | KAINOS MEDICINE, INC. (KR) | 2026-01-27 | — | — | US | disclosed |
| US-3953215-A | X-RAY FILM | FUJI PHOTO FILM CO., LTD. (JA) | 1976-04-27 | — | — | US | disclosed |
| US-3951666-A | CYANINE AND MEROCYANINE DYES | FUJI PHOTO FILM CO., LTD. (JA) | 1976-04-20 | — | — | US | disclosed |
| US-3945832-A | Fogged, direct-positive silver halide emulsion containing desensitizers and a dimethine optical sensitizing dye | FUJI PHOTO FILM CO., LTD. (JA) | 1976-03-23 | — | — | US | disclosed |
| US-3943142-A | Dye intermediates and their preparation and use in the synthesis of methine dyes | EASTMAN KODAK COMPANY (US) | 1976-03-09 | — | — | US | disclosed |
| US-3936308-A | Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus | EASTMAN KODAK COMPANY (US) | 1976-02-03 | — | — | US | disclosed |
| US-3935010-A | IMIDAZOQUINOXALINE DESENSITIZER | EASTMAN KODAK COMPANY (US) | 1976-01-27 | — | — | US | disclosed |
| US-3933507-A | LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER | AGFA-GEVAERT, A.G. (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570621-B2 | Short-acting 3,4-methylenedioxymethamphetamine (MDMA) analogs incorporating benzothiazole | SLC6A3, SLC6A2, HTR2C | NPC1 568/4885RAB9A 2541/4885MEN1 3915/4885 |
| US-12559485-B2 | CDK6/DYRK2 dual-target inhibitor, and preparation method therefor and use thereof | CDK6, CDK2, CDKL1 | NPC1 4401/4885RAB9A 2847/4885MEN1 1927/4885 |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | ABL1, TH, CYP3A43 | NPC1 1264/4885RAB9A 1131/4885MEN1 1574/4885 |
| US-12534452-B2 | N-(1H-imidazol-2-yl)benzamide compound and pharmaceutical composition comprising the same as active ingredient | IRAK4, IRAK1, IRAK2 | NPC1 880/4885RAB9A 2924/4885MEN1 2497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.