Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435188 | 0.68 | GAA (0.52) | GAAKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9302319 | 0.67 | KMT2A (0.54) | GAAKMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL17582661 | 0.64 | SMN1; SMN2 (0.43) | KMT2AKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1947320 | 0.63 | ADORA2B (0.39) | GAAKMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL8696414 | 0.61 | TYMP (0.41) | GAAKMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL10279638 | 0.61 | ALDH1A1 (0.34) | GAAKMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL10230420 | 0.61 | KDM4E (0.45) | L3MBTL1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL24097424 | 0.60 | ADORA2B (0.37) | GAAKMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL10178080 | 0.60 | CSNK2A2 (0.44) | GAAKMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL28143896 | 0.60 | TYMP (0.40) | GAAKMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314890-A | Treatment of asthma | MALESCI ISTITUTO FARMACOBIOLOGICO S.P.A. (IT) | 1994-05-24 | — | — | US | disclosed |
| EP-0531349-A1 | 1-7 SUBSTITUTED XANTHINE DERIVATIVES HAVING ANTIASTHMATIC ACTIVITY, THEIR SALTS PHYSIOLOGICALLY ACCEPTABLE, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | MALESCI ISTITUTO FARMACOBIOLOGICO S.p.A. (IT) | 1993-03-17 | — | — | EP | disclosed |
| WO-1991017993-A1 | 1-7 SUBSTITUTED XANTHINE DERIVATIVES HAVING ANTIASTHMATIC ACTIVITY, THEIR SALTS PHYSIOLOGICALLY ACCEPTABLE, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | MALESCI ISTITUTO FARMACOBIOLOGICO S.P.A (IT) | 1991-11-28 | — | — | WO | disclosed |