Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484348 | 0.86 | KMT2A (0.40) | ALDH1A1KMT2ALMNAHSD17B10 | |
| SCHEMBL10487994 | 0.83 | NPSR1 (0.44) | GSK3AGSK3BALOX15ALDH1A1KMT2A | |
| SCHEMBL10487966 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KMT2ARAB9AGAALMNA | |
| SCHEMBL10667971 | 0.74 | ALOX15 (0.45) | GSK3AGSK3BCA12CA9ALOX15 | |
| SCHEMBL9300692 | 0.68 | GSK3A (0.46) | GSK3AGSK3BCA12CA9ALOX15 | |
| SCHEMBL7454009 | 0.68 | ELANE (0.47) | GSK3AGSK3BALOX15ALDH1A1PIN1 | |
| SCHEMBL9708708 | 0.67 | GSK3A (0.49) | GSK3AGSK3BALOX15ALDH1A1PIN1 | |
| SCHEMBL11853714 | 0.67 | GSK3A (0.45) | GSK3AGSK3BCA12CA9ALOX15 | |
| SCHEMBL3384734 | 0.66 | GSK3A (1.00) | GSK3AGSK3BCA12CA9ALDH1A1 | |
| SCHEMBL2828076 | 0.66 | GAA (0.49) | GSK3AGSK3BALOX15ALDH1A1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0216324-B1 | 4-ALKOXY-3-PYRROLIN-2-ONE-1-YL-ACETIC ACID ALKYL AND BENZYL ESTERS AND THEIR PREPARATION | LONZA AG (CH) | 1990-11-22 | — | — | EP | claimed |
| US-4880940-A | 4-alkoxy-3-pyrrolin-2-on-1-yl acetic acid alkyl esters | LONZA LTD. (CH) | 1989-11-14 | — | — | US | claimed |
| US-5371237-A | Process for the production of 4-hydroxy-2-oxopyrrolidin-1-yl-acetamide | LONZA LTD. (CH) | 1994-12-06 | — | — | US | disclosed |
| US-5276164-A | Process for the production of 4-hydroxy-2-oxopyrrolidin-1-yl-acetamide | LONZA LTD. (CH) | 1994-01-04 | — | — | US | disclosed |
| US-4880940-A | 4-alkoxy-3-pyrrolin-2-on-1-yl acetic acid alkyl esters | LONZA LTD. (CH) | 1989-11-14 | — | — | US | disclosed |
| US-4824966-A | Process for the production of 4-hydroxy-2-oxo-pyrrolidin-1-yl acetamide | LONZA LTD. (CH) | 1989-04-25 | — | — | US | disclosed |
| US-4780545-A | Production of 4-alkoxy-3-pyrrolin-2-on-1-yl acetic acid alkyl esters | LONZA LTD. (CH) | 1988-10-25 | — | — | US | disclosed |