Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300804 | 0.86 | GSK3A (0.49) | KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL9302170 | 0.85 | LMNA (0.36) | KMT2ASMN1; SMN2KDM4ETDP1ALDH1A1 | |
| SCHEMBL10777317 | 0.83 | TSHR (0.39) | KMT2ATSHR | |
| SCHEMBL10487994 | 0.81 | NPSR1 (0.44) | KMT2AL3MBTL1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL10487966 | 0.79 | ALDH1A1 (0.44) | KMT2AL3MBTL1SMN1; SMN2TDP1TSHR | |
| SCHEMBL10583879 | 0.78 | ALDH1A1 (0.43) | KMT2AL3MBTL1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL21341572 | 0.75 | CA1 (0.34) | — | |
| SCHEMBL10664489 | 0.74 | KMT2A (0.36) | KMT2AL3MBTL1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL4921842 | 0.74 | ALDH1A1 (0.34) | KMT2AL3MBTL1KDM4ETSHRALDH1A1 | |
| SCHEMBL9823072 | 0.66 | TSHR (0.44) | KMT2AL3MBTL1SMN1; SMN2KDM4EKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880940-A | 4-alkoxy-3-pyrrolin-2-on-1-yl acetic acid alkyl esters | LONZA LTD. (CH) | 1989-11-14 | — | — | US | claimed |
| US-4880940-A | 4-alkoxy-3-pyrrolin-2-on-1-yl acetic acid alkyl esters | LONZA LTD. (CH) | 1989-11-14 | — | — | US | disclosed |
| US-4879393-A | 4-Benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-11-07 | — | — | US | disclosed |
| US-4877884-A | 4-benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-10-31 | — | — | US | disclosed |
| US-4868314-A | 4-benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-09-19 | — | — | US | disclosed |
| US-4849528-A | 4-HYDROXYPYRROLIDIN-2-ON-1-YLACETAMIDE, INTERMEDIATE | LONZA LTD. (CH) | 1989-07-18 | — | — | US | disclosed |
| US-4843166-A | 4-benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-06-27 | — | — | US | disclosed |
| US-4780545-A | Production of 4-alkoxy-3-pyrrolin-2-on-1-yl acetic acid alkyl esters | LONZA LTD. (CH) | 1988-10-25 | — | — | US | disclosed |