Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.43 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31256472 | 0.78 | ALDH1A1 (0.69) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL372102 | 0.77 | PIM1 (0.43) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL9300813 | 0.77 | HIF1A (0.38) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL28892080 | 0.74 | CDK2 (0.44) | PTPN11RNASEH1GPR35ATG4BMEN1 | |
| SCHEMBL29032121 | 0.73 | SRC (0.40) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL2114515 | 0.73 | PTPN22 (0.50) | ALDH1A1KDM4EMAPTALOX15HSD17B10 | |
| SCHEMBL11107827 | 0.69 | PTPN22 (0.63) | PTPN11RNASEH1GPR35ATG4BMEN1 | |
| SCHEMBL18068463 | 0.69 | PTPN22 (0.56) | ALDH1A1KDM4EMAPTALOX15RECQL | |
| SCHEMBL16816392 | 0.68 | CASP6 (0.47) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL20356048 | 0.67 | MGAM (0.47) | PTPN11RNASEH1GPR35ATG4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276174-A | Alk-1-enyloxy carbonates | ISP INVESTMENTS INC. (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0514482-A4 | VINYL ETHER COMPOUNDS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0514482-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991013052-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1991-09-05 | — | — | WO | disclosed |