Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
| ▸ | CDC42 | P60953 | 2/20 | 0.35 |
| ▸ | RAC1 | P63000 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | PRKACA | P17612 | 2/20 | 0.33 |
| ▸ | PRKACG | P22612 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL372102 | 0.79 | PIM1 (0.43) | HIF1AEPAS1PTPN22PIM1KDM4E | |
| SCHEMBL9300809 | 0.77 | PTPN11 (0.43) | PTPN22PIM1KDM4EALDH1A1GAA | |
| SCHEMBL20356047 | 0.75 | HIF1A (0.54) | HIF1AEPAS1PTPN22CDC42RAC1 | |
| SCHEMBL29032121 | 0.75 | SRC (0.40) | HIF1AEPAS1PTPN22PIM1KDM4E | |
| SCHEMBL2114515 | 0.75 | PTPN22 (0.50) | PTPN22CDC42RAC1KDM4EALDH1A1 | |
| SCHEMBL16641054 | 0.72 | HIF1A (0.52) | HIF1AEPAS1PTPN22CDC42RAC1 | |
| SCHEMBL109169 | 0.70 | PTPN22 (0.39) | HIF1AEPAS1PTPN22KDM4EALDH1A1 | |
| SCHEMBL16816392 | 0.70 | CASP6 (0.47) | HIF1APTPN22KDM4EALDH1A1MAPT | |
| SCHEMBL2113130 | 0.69 | BACE1 (0.36) | ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL7923734 | 0.68 | PTPN22 (0.48) | PTPN22PIM1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276174-A | Alk-1-enyloxy carbonates | ISP INVESTMENTS INC. (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0514482-A4 | VINYL ETHER COMPOUNDS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0514482-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991013052-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1991-09-05 | — | — | WO | disclosed |