Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | IAPP | P10997 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28493644 | 0.89 | KMT2A (0.47) | KMT2APOLBCTDSP1MEN1KDM4E | |
| SCHEMBL4541922 | 0.83 | ALDH1A1 (0.48) | KMT2APOLBMEN1L3MBTL1IAPP | |
| SCHEMBL3868190 | 0.83 | KMT2A (0.49) | KMT2APOLBCTDSP1MEN1L3MBTL1 | |
| SCHEMBL1449785 | 0.83 | MEN1 (0.52) | KMT2AMEN1L3MBTL1KDM4EGLA | |
| SCHEMBL9709577 | 0.82 | IAPP (0.59) | POLBCTDSP1IAPP | |
| SCHEMBL106914 | 0.82 | CA2 (0.54) | L3MBTL1KDM4EIAPPTDP1EGFR | |
| SCHEMBL5548416 | 0.82 | IAPP (0.44) | POLBL3MBTL1KDM4EIAPPTDP1 | |
| SCHEMBL1411319 | 0.82 | L3MBTL1 (0.62) | KMT2AMEN1L3MBTL1IAPPTDP1 | |
| SCHEMBL6103810 | 0.82 | MEN1 (0.44) | KMT2AMEN1L3MBTL1KDM4EGLA | |
| SCHEMBL7256785 | 0.80 | ALDH1A1 (0.49) | KMT2APOLBCTDSP1MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113825748-A | Antimicrobial compounds and methods | 库扎环球有限责任公司 | 2021-12-21 | — | — | CN | disclosed |
| EP-3911643-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | Curza Global LLC (US) | 2021-11-24 | — | — | EP | disclosed |
| CN-110208414-B | Analysis method for quantitatively determining more than target flavor components in tobacco | 中国烟草总公司郑州烟草研究院 | 2021-10-15 | — | — | CN | disclosed |
| CN-110133156-B | Analysis method for high-throughput determination of multi-target aroma components in electronic cigarette liquid | 中国烟草总公司郑州烟草研究院 | 2021-10-15 | — | — | CN | disclosed |
| CN-110133155-B | Gas chromatography-tandem mass spectrometry analysis method of tobacco essence and flavor | 中国烟草总公司郑州烟草研究院 | 2021-09-14 | — | — | CN | disclosed |
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |
| WO-2017107052-A1 | SOLUBLE GUANYLATE CYCLASE STIMULATORS | MERCK SHARP & DOHME CORP. (US) | 2017-06-29 | — | — | WO | disclosed |
| US-5356893-A | Antidepressants, nervous system disorders | GLAXO GROUP LIMITED (GB) | 1994-10-18 | — | — | US | disclosed |
| EP-0533266-A1 | Benzanilide derivatives as 5-HT1D antagonists | GLAXO GROUP LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |