Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625450 | 0.88 | SRD5A2 (0.47) | FFAR1VCPOPRD1CACNA2D1CACNB2 | |
| SCHEMBL17845069 | 0.84 | APP (0.48) | MAPTFFAR1HPGDLMNAALDH1A1 | |
| SCHEMBL2519799 | 0.80 | TSHR (0.52) | MAPTFFAR1HPGDLMNAALDH1A1 | |
| SCHEMBL2801832 | 0.80 | TSHR (0.52) | MAPTFFAR1HPGDLMNAALDH1A1 | |
| SCHEMBL2686081 | 0.80 | VCP (0.46) | MAPTSMN1; SMN2FFAR1HPGDLMNA | |
| SCHEMBL400497 | 0.79 | MAPT (0.59) | MAPTSMN1; SMN2FFAR1HPGDLMNA | |
| SCHEMBL9299537 | 0.78 | ALOX5 (0.45) | FFAR1 | |
| SCHEMBL8681264 | 0.78 | CYP1A1 (0.44) | MAPTFFAR1HPGDALDH1A1CACNA2D1 | |
| SCHEMBL9299320 | 0.77 | ALDH1A1 (0.43) | MAPTFFAR1HPGDLMNAALDH1A1 | |
| SCHEMBL2683928 | 0.76 | CACNA2D1 (0.40) | MAPTFFAR1HPGDALDH1A1CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326902-A | Oxyalkyne compounds, pharmaceutical compositions containing them and processes for preparing such compounds and compositions | GRUENENTHAL GMBH (DE) | 1994-07-05 | — | — | US | disclosed |