Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | UBE2M | P61081 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301234 | 0.94 | HPGD (0.47) | HPGDEPHX2HSD11B1MGLLLMNA | |
| SCHEMBL9302070 | 0.85 | EPHX2 (0.47) | HPGDEPHX2HSD11B1MGLLLMNA | |
| SCHEMBL9302730 | 0.83 | EPHX2 (0.51) | HPGDEPHX2HSD11B1MGLLLMNA | |
| SCHEMBL9302303 | 0.79 | EPHX2 (0.47) | HPGDEPHX2HSD11B1MGLLLMNA | |
| SCHEMBL14003455 | 0.78 | HPGD (0.64) | HPGDEPHX2HSD11B1MGLLLMNA | |
| SCHEMBL9301100 | 0.77 | HPGD (0.53) | HPGDEPHX2HSD11B1MGLLLMNA | |
| SCHEMBL9302354 | 0.76 | EPHX2 (0.45) | HPGDEPHX2HSD11B1MGLLLMNA | |
| SCHEMBL23417314 | 0.76 | HPGD (0.64) | HPGDEPHX2HSD11B1MGLLLMNA | |
| SCHEMBL9301438 | 0.75 | ACHE (0.51) | LMNAKMT2AALDH1A1MEN1CHRM1 | |
| SCHEMBL9551866 | 0.74 | HPGD (0.52) | HPGDEPHX2HSD11B1MGLLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| JP-5221982-A | — | — | None | — | — | JP | disclosed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |
| JP-H05221982-A | DERIVATIVE OF 4-AMINOMETHYLPIPERIDINE, ITS PREPARATION AND ITS APPLICATION FOR TREATMENT | PIERRE FABRE MEDICAMENT | 1993-08-31 | — | — | JP | disclosed |