Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301418 | 0.91 | ACHE (0.43) | EPHX2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9302183 | 0.90 | CYP2D6 (0.44) | UBE2MDCUN1D1HSD11B1MGLLKMT2A | |
| SCHEMBL9301890 | 0.89 | L3MBTL1 (0.46) | HPGDLMNAUBE2MDCUN1D1HSD11B1 | |
| SCHEMBL9302303 | 0.84 | EPHX2 (0.47) | EPHX2HPGDLMNAUBE2MDCUN1D1 | |
| SCHEMBL9302070 | 0.84 | EPHX2 (0.47) | EPHX2HPGDLMNAUBE2MDCUN1D1 | |
| SCHEMBL9302730 | 0.83 | EPHX2 (0.51) | EPHX2HPGDLMNAUBE2MDCUN1D1 | |
| SCHEMBL9301877 | 0.80 | BACE1 (0.43) | LMNADCUN1D1KMT2AMEN1CHRM1 | |
| SCHEMBL9302364 | 0.77 | EPHX2 (0.46) | EPHX2HPGDLMNAUBE2MDCUN1D1 | |
| SCHEMBL9301097 | 0.76 | HPGD (0.51) | EPHX2HPGDLMNAUBE2MDCUN1D1 | |
| SCHEMBL9301986 | 0.74 | CYP2D6 (0.46) | UBE2MDCUN1D1HSD11B1MGLLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |