Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GPR6 | P46095 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303169 | 0.93 | ACHE (0.47) | ACHEBACE1DRD4DRD2BCHE | |
| SCHEMBL9301861 | 0.82 | BACE1 (0.49) | ACHEBACE1DRD4DRD2BCHE | |
| SCHEMBL9301121 | 0.78 | ACHE (0.45) | ACHEBACE1DRD4BCHECXCR4 | |
| SCHEMBL9301443 | 0.76 | CXCR4 (0.65) | ACHEBACE1DRD4DRD2BCHE | |
| SCHEMBL9301877 | 0.75 | BACE1 (0.43) | ACHEBACE1DRD4DRD2BCHE | |
| SCHEMBL9301097 | 0.75 | HPGD (0.51) | LMNAALDH1A1CHRM1MEN1KMT2A | |
| SCHEMBL13202585 | 0.74 | ACHE (0.67) | ACHEBACE1DRD4BCHECXCR4 | |
| SCHEMBL9303177 | 0.73 | CXCR4 (0.60) | ACHEBACE1DRD4DRD2BCHE | |
| SCHEMBL156415 | 0.72 | ACHE (0.67) | ACHEBACE1BCHECXCR4ALDH1A1 | |
| SCHEMBL12447 | 0.72 | BACE1 (0.59) | ACHEBACE1DRD4DRD2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |