Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301405 | 0.90 | ACHE (0.46) | EPHX2KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL9301986 | 0.90 | CYP2D6 (0.46) | HSD11B1MGLLKMT2AMEN1UBE2M | |
| SCHEMBL9301293 | 0.89 | LMNA (0.46) | EPHX2HSD11B1MGLLNPC1RAB9A | |
| SCHEMBL9301620 | 0.87 | RBP4 (0.48) | HPGDHSD11B1MGLLKMT2ALMNA | |
| SCHEMBL9302730 | 0.87 | EPHX2 (0.51) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL9302070 | 0.86 | EPHX2 (0.47) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL9301807 | 0.86 | TSHR (0.45) | HPGDHSD11B1KMT2AMEN1UBE2M | |
| SCHEMBL9302354 | 0.84 | EPHX2 (0.45) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL9302654 | 0.80 | EPHX2 (0.45) | EPHX2HSD11B1MGLLKMT2ALMNA | |
| SCHEMBL9301097 | 0.79 | HPGD (0.51) | EPHX2HPGDHSD11B1MGLLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |