Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.70 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | DRD4 | P21917 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301892 | 0.90 | KMT2A (0.67) | KMT2AKCNH2CACNA1GL3MBTL1MEN1 | |
| SCHEMBL11365346 | 0.89 | KCNH2 (0.86) | KMT2AKCNH2CACNA1GL3MBTL1DRD4 | |
| SCHEMBL13621747 | 0.87 | CACNA1G (0.87) | KMT2AKCNH2CACNA1GL3MBTL1MEN1 | |
| SCHEMBL31510197 | 0.87 | KMT2A (0.66) | KMT2AKCNH2CACNA1GL3MBTL1MEN1 | |
| SCHEMBL11240406 | 0.83 | L3MBTL1 (0.97) | KMT2AL3MBTL1MEN1DRD4KDM4E | |
| SCHEMBL3970369 | 0.83 | L3MBTL1 (0.97) | KMT2AL3MBTL1MEN1DRD4KDM4E | |
| SCHEMBL4577971 | 0.83 | L3MBTL1 (0.97) | KMT2AL3MBTL1MEN1DRD4KDM4E | |
| SCHEMBL9192429 | 0.83 | KCNH2 (0.64) | KMT2AKCNH2CACNA1GL3MBTL1DRD4 | |
| SCHEMBL22639683 | 0.82 | ATM (0.85) | KMT2AKCNH2CACNA1GKDM4EMAPT | |
| SCHEMBL7953079 | 0.82 | ATM (0.85) | KMT2AKCNH2CACNA1GKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342839-A | Useful for therapy of oxygen deficiency diseases of the brain | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |
| EP-0435902-A1 | 2-HYDROXY-3-PHENOXY-PROPYL-SUBSTITUTED PIPERAZINES AND HOMOPIPERAZINES, THEIR MANUFACTURE AND USE. | BASF AG (DE) | 1991-07-10 | — | — | EP | disclosed |
| WO-1990003371-A1 | 2-HYDROXY-3-PHENOXY-PROPYL-SUBSTITUTED PIPERAZINES AND HOMOPIPERAZINES, THEIR MANUFACTURE AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1990-04-05 | — | — | WO | disclosed |